LOL that seems a bit ridiculous, although I do admit my mouse-hand does get sweaty during long play sessions. And I do like the idea of modifying the weight of the mouse itself. Most mice are too light, imho.
Speaking of mice, I got the
Razer Naga Hex when D3 came out and have been loving it. I've sworn by the Logitech MX 5-series for a long time (since before WoW, IIRC), and even bought 3 extra just in case they stopped making them or tweaked the design for the worse. But I've found the Naga Hex perfect for D3 since the side buttons map directly to your keyboard's 1-6 keys. I use my left hand for the shift key, and that's it. I'll play single-handedly many times, if I'm trying to eat or whatever at the same time. Recommended.